Toxicology

Drug Testing for Pain and Addiction Management

Many medicines that are prescribed for pain management to improve quality of life are found to be taken incorrectly, abused, or are sold for profit. There are substances available for illicit use, including prescription and/or nonprescription drugs, to ensure safe and effective therapy. It is recommended that patients be monitored for prescribed medication(s) and non-prescribed drugs through periodic drug tests. Drug testing can determine the presence or absence of drugs and/or drug metabolites. We are committed to creating a customized urine drug testing panel for the specific needs of our clients for medication monitoring and addiction treatment.

Genesis Lab has a two-step testing procedure for all the samples. After initial screening with an Immunoassay (qualitative) test for presumptive positive and adulterant, a confirmation (quantitative) test is performed using UPLC MS/MS (liquid chromatography/mass spectrometry/mass spectrometry).


Ultra-performance liquid chromatography Tandem mass spectrometer (UPLC/MS/MS) is the most powerful technique used, which has a very high sensitivity and selectivity. UPLC/MS/MS is at the Platinum Standard for drug identification.

  • Amphetamine
  • Barbiturate
  • Benzodiazepine
  • Buprenorphine
  • Cocaine
  • Cannabinoid (THC)
  • Meperidine
  • Methadone
  • 6-AM (Heroin Metabolite)
  • Opiate
  • Oxycodone
  • Phencyclidine (PCP)
  • Ethyl Alcohol
  • Fentany
The Following Adulterants
Are Tested for:
Creatinine
pH
Oxidant
Nitrite
Specific Gravity

Natural and Semi Synthetic Opioids


  • Buprenorphine / Naloxone / Norbuprenorphine
  • Codeine / Dihydrocodeine
  • Morphine
  • Hydrocodone / Norhydrocodone
  • Hydromorphone
  • Oxycodone / Noroxycodone
  • Oxymorphone

Barbiturates


  • Butalbital
  • Phenobarbital

Synthetic Opioids


  • Methadone / EDDP
  • Fentanyl / Norfentanyl
  • Meperidine
  • Tapentadol
  • Tramadol / O-Desmethyltramadol

Tricyclics / Antidepressants


  • Amitriptyline
  • Nortriptyline
  • Doxepin
  • Desipramine
  • Imipramine

Benzodiazepines


  • Alprazolam / A-Hydroxyalprazolam
  • Diazepam / Nordiazepam/Oxazepam
  • Temazepam
  • Clonazepam / 7-aminoclonazepam
  • Lorazepam
  • Flunitrazepam
  • Desalkylflurazepam

Alcohol


  • ETS
  • ETG

Illicit Drugs


  • 6-MAM (Heroin)
  • Benzoylecgonine (Cocaine Metabolite)
  • PCP
  • THC-COOH
  • MDMA
  • MDA

Amphetamines/Stimulants


  • Amphetamine
  • Methamphetamine

Average Window of Detection for Drugs of Abuse

Amphetamines2-4 days
Barbiturates1-3 days (Phenobarbital., 2 weeks)
BenzodiazepinesUp to 2 weeks
Cocaine (BE)2-3 days
Methadone (EDDP)2-4 days
Opiates2-3 days
Oxycodone1-3 days
Phencyclidine3-8 days
Heroin Metabolite (6-MAM)12-24 hours
EthanolLess than 1 day
THC1-95 days

Therapeutic drug monitoring is the measurement of specific drugs at timed intervals in order to maintain a relatively constant concentration of the medication in the bloodstream. This test is used for physicians to adjust patient medication to optimize therapy and reduce the risk of toxicity.

Therapeutic Drugs Monitoring Test Menu

  • Amikacin
  • Carbamazepine
  • Cyclosporine
  • Digoxin
  • Disopyramide
  • Ethosuximide
  • Gabapentin
  • Gentamicin
  • Levetiracetam
  • Lidocaine
  • Methotrexate
  • Mycophenolic acid
  • Phenobarbital
  • Phenytoin
  • Procainamide
  • Theophylline
  • Tobramycin
  • Topiramate
  • Valproic Acid
  • Vancomycin
  • Zonisamide